Blood thinner drugs can help treat Covid-19 patients, leading British doctors have found, who hope for a major breakthrough in the race to find a cure for the deadly virus.
Experts in London achieved this success after discovering that coronaviruses triggered potentially fatal blood clots in each critically ill patient that they tested using pioneering scanning technology.
NHS England is set to release hospitals with new guidance on blood thinning, which is likely to eventually lead to carefully higher doses for seriously ill people.
Prof. Peter Openshaw who is part of the government's scientific advisory group for emergencies (SEZ) on clinical information, said a lot of collaboration between scientists uncovered an unprecedented story about the virus where we knew nothing about previously.
Medical officials at the Royal Brompton Hospital's Severe Respiratory Failure Service established the closest connection yet between Covid-19 and clot using high-tech dual-energy CT scans to capture images of lung function in their most severe patients. All those tested were suffering from a lack of blood flow, allowing clots to form within small vessels in the lungs. This partly explains why some patients are dying of lung failure through lack of oxygen in the blood, doctors told media outlets. Low oxygen levels have been routinely reported in Kovid patients who are reporting without breathlessness.
Prof. Openshaw, an expert in experimental medicine at Imperial and Honorary Physician at St. Marys Hospital stated 'This intravascular clotting is a really bad twist that we haven't seen before with many other viruses.'
'This explains the extraordinary clinical picture that is being seen with people being very hypoxic, very low on oxygen, and not really particularly breathing. This is the origin of the blood vessel Will fit with. '
New proof implies that randomized clinical preliminaries to test blood-thinning or anticoagulant operators of COVID patients are presently being optimized as a major aspect of the administration's critical research portfolio into potential answers for worldwide wellbeing crises. The new NHS England direction is free of this work and is accepted to have been given on the exhortation of hematology specialists.
The doctors involved in the findings at Royal Brompton underscored the need for the careful use of blood-thinning medication, which can have fatal consequences. Leading experts warn that the use of anticoagulants should be a "personalized approach" by physicians. Any treatment will need to be "started very early" to prevent clots from forming.
A senior intensive physician at Royal Brompton and Imperial, Drs. Brijesh Patel stated 'I think most patients will end up at significant therapeutic doses of blood-thinning agents as we learn more about the disease. If certain interventions in the blood are implemented appropriately they will save lives.'
Dr. Patel stated 'I think it is important to introduce blood-thinning agents associated with Kovid, but you have to do it properly, otherwise you can cause harm.'
(LMWH) Low molecular weight heparin medical supplements used to reduce the risk of clots, deep vein thrombosis, and pulmonary embolism are already regularly used in small amounts for hospital patients due to the length of time patients spend lying in beds.
Dr. Patel's team treated and studied more than 150 of Britain's most critically ill patients. Using high-tech CT scans, they quickly established that lung injury was "much more pronounced" in Kovid victims than it would be in other patients suffering from lung failure. The doctors will publish their preliminary findings next week.
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